MOLECULAR NET DIAGNOSTIC
A liquid biopsy neuroendocrine tumor diagnostic to help oncologists better manage NETs
The NETest is a blood-based neuroendocrine cancer diagnostic that aids in the diagnosis, treatment recommendation, and real-time progress monitoring of patients with neuroendocrine tumors (NET) or neuroendocrine neoplasia (NEN).
Quick and non-invasive, results from this novel liquid biopsy can be shared within 48 hours of receiving a blood sample. Once received at our CAP and CLIA-certified lab, we utilize a quantitative polymerase chain reaction (qPCR) method to measure the expression levels of 51 genes associated with neuroendocrine cancer. Subsequently, our multianalyte algorithmic analyses (MAAA) are employed to calculate the probability of a patient having a neuroendocrine tumor (NET) or neuroendocrine neoplasia (NEN). The obtained likelihood or risk score is then available. Learn more about Our Science.
The NETest, which has been used over 10,000 times in medical centers throughout the United States, delivers higher levels of sensitivity, specificity, and accuracy than any other testing method available today. It helps oncologists and patients better manage and monitor treatment and quickly detect the recurrence of disease.
NETest by the Numbers
Prior to and since its introduction in 2014, the NETest has been the subject of 63 peer-reviewed articles, clinical studies, and scientific journal entries. With over a decade of research and over 10,000 use cases in the US alone, the empirical evidence is clear: NETest outperforms all other molecular and non-molecular biomarkers in the diagnosis and management of neuroendocrine tumors.
10,000+ NETests Utilized
Prominent Oncologists Worldwide have Recommended and Utilized the NETest
Since the first commercial sale of the NETest shortly after our founding in 2014, over 10,000 NETests have been used by doctors and oncologists affiliated with some of the most well-respected Cancer Centers across the United States. Visit our NETest Resources Page to learn more
View a Sample Test
Interested in seeing a sample lab report for the NETest, detailing test methodology, score calculation, and sample NETest results? Then click below to download the PDF.
Are you a doctor, or a patient working with a doctor or oncologist, and would like to order a NETest? Then click the link below for our online requisition.
Featured NETest Resources
The latest Peer-Reviewed Papers and News Coverage of the NETest
Analysis of ten studies indicates the NETest is an accurate (>95%) biomarker suitable for clinical use in NET disease management, exhibiting utility as an IVD to establish a diagnosis and monitor therapeutic efficacy.
The NETest PPQ–Peptide Receptor Radionuclide Therapy Predictor Quotient–exhibits over 97% accuracy in predicting positive response to PRRT for metastatic/inoperable NETs in real time.
Neuroendocrine Neoplasia Diagnosis: mRNA biomarker NETest exhibits 3-5 times greater accuracy than Chromogranin A
NETest, a multigenomic mRNA biomarker exhibiting ~99% accuracy in NEN disease identification; is far more accurate than CgA (19–33%) and should be considered the biomarker standard of care.
An interview with the Co-Inventor of the NETest
“The NETest fulfills a completely unmet need in neuroendocrine tumor disease: there have been no biomarkers that are effective or accurate. This is a multi-genomic test and it is about 95% accurate and 95% sensitive. It makes the diagnosis of neuroendocrine tumors, then allows you to monitor neuroendocrine tumors to see if the disease is stable or progressive.”
Dr. Irvin M. Modlin
Founder of Wren Laboratories and co-developer of the NETest
HOW IT WORKS
The NETest Testing Process
LOCAL LAB & DR. OFFICE
A Non-Invasive Blood Draw
Obtain a requisition in conjunction with your doctor, then get your blood sample drawn at a local laboratory.
The blood sample with the requisition form is sent overnight to the clinical testing laboratory at Wren Laboratories, Branford, CT.
Testing is Performed
The laboratory performs all testing necessary to generate a NETest result – a process that typically takes two full days.
Results are Generated
Once the resuls are produced and verified, the NETest report is sent to your doctor.
CLINICAL INSTITUTION / DOCTOR’S OFFICE
Your doctor interprets the NETest result in conjunction with other clinical assessments.
The patient is notified of the results.